Download A4Medicine Mobile App
Empower Your RCGP AKT Journey: Master the MCQs with Us! 🚀
Raised blood sugar in patients with known diabetes is a frequent challenge in primary care, requiring prompt and systematic assessment to prevent acute complications such as diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS) while addressing chronic control. As primary care clinicians, you often encounter these cases in triage settings with limited access to full patient records, relying on recent results (e.g., HbA1c, prior glucose readings, out-of-hours encounters) to guide decisions.
This stepwise triage guide provides a structured approach to evaluate and manage elevated blood glucose levels, using both mmol/L and mg/dL units for clarity. It emphasizes identifying urgent cases, leveraging available data, and ensuring patient safety through timely intervention and clear follow-up. The following steps aim to balance efficiency with thoroughness, enabling you to differentiate between routine hyperglycemia and emergencies while supporting patient education and continuity of care.
Q: What is the patient's current blood glucose level and how was it measured (fingerstick/lab)?
Action: If no recent reading, request a capillary test. >22.2 mmol/L (>400 mg/dL) may indicate acute risk.
Q: Symptoms: Nausea, vomiting, breathlessness, confusion?
Action: Check capillary blood ketones or urine. If >1.5 mmol/L or urine moderate/large → urgent ED referral.
Q: Recent HbA1c and blood glucose trends?
Action: If not available, use current CBG + symptoms to guide triage.
Q: Missed any meds (e.g., insulin, metformin)? Started steroids?
Action: Resume meds if appropriate. Adjust insulin doses in consultation.
Q: Infection? High-carb intake? Stress? Reduced activity?
Action: Treat cause. Reinforce hydration, monitoring, and sick-day rules.
Q: History of retinopathy, nephropathy, CVD, or HF?
Action: Escalate earlier if comorbid or vulnerable.
Action: Escalate appropriately. Adjust meds or monitor at home with follow-up.
Q: Does the patient understand how to monitor, hydrate, and when to seek help?
Action: Book GP/diabetes nurse f/u in 48–72 hrs. Document advice.
PRN insulin use for raised blood glucose in clinically well patients with diabetes.
Patient Group | CBG Target (mmol/L) | CBG Target (mg/dL) |
---|---|---|
Standard Adult | 6–10 | 108–180 |
Frail / Elderly / EoL | 6–15 | 108–270 |
Only consider PRN insulin if CBG >18.0 mmol/L (>324 mg/dL)
Assess individual risk: frailty, insulin sensitivity, current regimen
Avoid bedtime PRNs in elderly (higher hypoglycemia risk)
CBG (mmol/L) | CBG (mg/dL) | Suggested PRN Dose |
---|---|---|
18.1 – 25.0 | 325 – 450 | 4 units Novorapid® / Trurapi® (subcut) |
≥ 25.1 | ≥ 451 | 6 units Novorapid® / Trurapi® (subcut) |
Dose reduction (e.g., 2–4 units) advised for frail or insulin-sensitive patients
Expected glucose drop: ~3 mmol/L (~54 mg/dL) per unit
Check capillary blood glucose:
2 hours post-PRN dose
4 hours post-PRN dose
PRN Use Over 48 Hours | Recommended Action |
---|---|
No doses required | 🛑 Stop PRN insulin |
1 dose given | ✅ Continue PRN, review daily |
≥2 doses given | ⚠️ Review insulin plan; consider titration or specialist input |
Always consider patient context before prescribing PRN insulin.
Document indication, dose, and timing clearly.
Liaise with diabetes specialist if frequent corrections are needed.
Let me know if you'd like this formatted for print or integrated into a patient safety checklist.
References
University Hospitals of Leicester NHS Trust. Hyperglycaemia in Adult Inpatients with Diabetes – including Decision Support Tool (UHL Guideline). Updated 2023. Accessed June 2025.
https://secure.library.leicestershospitals.nhs.uk/PAGL/Shared%20Documents/Hyperglycaemia%20in%20Adult%20Inpatients%20with%20Diabetes%20-%20including%20Decision%20Support%20Tool%20UHL%20Guideline.pdf
National Institute for Health and Care Excellence (NICE). Diabetic ketoacidosis in adults. NICE guideline NG17. 2015.
https://www.nice.org.uk/guidance/ng17
Joint British Diabetes Societies (JBDS) for Inpatient Care. The Management of the Hyperosmolar Hyperglycaemic State (HHS) in Adults with Diabetes. 2021 Update.
https://abcd.care/sites/abcd.care/files/site_uploads/JBDS-HHS-2021.pdf
American Diabetes Association. Standards of Medical Care in Diabetes—2024. Diabetes Care. 2024;47(Suppl 1):S1–S212.
https://doi.org/10.2337/dc24-S001