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Knee Pain in Adults - Remote triage

Knee pain is a prevalent and growing public health concern, particularly among adults, making it one of the most frequent reasons for primary care consultations. Research indicates that nearly 25% of Americans over the age of 55 experience chronic knee pain, with osteoarthritis (OA) being the leading cause (Hunter et al., 2022). This condition not only contributes to reduced mobility and disability but also imposes significant financial burdens, with knee OA-related medical costs surpassing $80 billion annually (Shema-Shiratzky et al., 2023).


As the aging population continues to rise, primary care providers play a critical role in early diagnosis, risk assessment, and effective management of knee pain. While osteoarthritis accounts for approximately 13.8% of cases, other contributing factors include previous knee injuries, inflammatory conditions, and psychosocial influences (Bedenbaugh et al., 2021; Sugai et al., 2018). Risk factors such as age, obesity, and prior trauma can negatively impact treatment outcomes, making a comprehensive and multidisciplinary approach essential for optimal patient care (Collier et al., 2023).


Knee Pain Triage Questionnaire

Knee Pain Triage Questionnaire


1. General Information

2. Pain Characteristics

3. Mechanical Symptoms

4. Functional Impact

5. Red Flag Symptoms

6. Self-Examination Maneuvers

7. Previous Treatments & Medications

8. Patient Concerns & Expectations



In summary, knee pain remains a prevalent complaint in the adult population presented to primary care physicians. With a multifactorial nature, underlying causes predominantly include osteoarthritis and previous injuries alongside psychological factors affecting pain perception. Addressing the growing burden of knee pain will require enhanced awareness and innovative treatment strategies within primary care.


Key differentials to consider include


Cause Key Features/Description Primary Care Considerations
Osteoarthritis Degenerative joint disease; pain worsens with activity; common in older adults.
  • Recommend weight loss, exercise, physical therapy.
  • Use NSAIDs/acetaminophen for pain control.
  • Obtain weight-bearing X-rays for assessment.
Rheumatoid Arthritis Autoimmune inflammatory disorder; symmetrical joint involvement, swelling, warmth, morning stiffness.
  • Labs: ESR(↑), CRP(↑), Rheumatoid factor, Anti-CCP.
  • Coordinate with rheumatology for DMARD therapy.
  • Address comorbidities and monitor for systemic manifestations.
Meniscal Tears Injury to knee cartilage (often twisting motion). Symptoms include locking, catching, joint line tenderness.
  • Perform McMurray’s test.
  • Consider MRI if mechanical symptoms persist.
  • Conservative management first (rest, NSAIDs, PT) before surgical referral.
Ligament Injuries ACL, PCL, MCL, or LCL damage from pivoting/trauma. Presents with instability, swelling.
  • Assess with Lachman, drawer, varus/valgus stress tests.
  • MRI if suspicion is high.
  • Refer for severe tears or instability.
Patellofemoral Pain Syndrome “Runner’s knee.” Anterior knee pain worsened by stair climbing, prolonged sitting, malalignment.
  • Focus on quadriceps strengthening and activity modification.
  • Assess patellar tracking and foot alignment.
  • Consider physical therapy if persistent.
Patellar Tendinitis “Jumper’s knee.” Overuse inflammation of patellar tendon, localized below kneecap.
  • Recommend rest, ice, activity modification.
  • Physical therapy with eccentric quadriceps exercises.
  • NSAIDs for pain and inflammation.
Bursitis Inflammation of fluid-filled sacs (prepatellar, pes anserine). Localized swelling, tenderness.
  • Common with overuse or prolonged kneeling.
  • NSAIDs, rest, aspiration if large effusion.
  • Check for infection if redness or warmth is present.
Gout / Pseudogout Crystal-induced arthropathies; acute severe pain, swelling, redness. Gout (urate↑), Pseudogout (CPPD crystals).
  • Joint aspiration for definitive diagnosis (monosodium urate vs. CPP crystals).
  • Acute management with NSAIDs, colchicine, or steroids.
  • Long-term management (gout) may require urate-lowering therapy.
Septic Arthritis Infection within the joint. Severe pain, redness, swelling, fever, inability to bear weight.
  • Labs: ESR(↑), CRP(↑). Urgent joint aspiration for Gram stain, culture.
  • Rapid antibiotic treatment and orthopedic consult.
Referred Pain Pain originating from hip or lumbar spine pathology but felt in the knee.
  • Perform a thorough hip and spine exam.
  • Knee imaging may be normal.
  • Consider imaging of the hip or spine when clinical suspicion is high.





References

  • Almeida, B., Capela, A., Pinto, J., Santos, V., Silva, C., & Rosa, M. (2019). Relationship between the perceived social support and catastrophization in individuals with chronic knee pain. Brazilian Journal of Pain, 2(1). https://doi.org/10.5935/2595-0118.20190011

  • Bedenbaugh, A., Bonafede, M., Marchlewicz, E., Lee, V., & Tambiah, J. (2021). Real-world health care resource utilization and costs among US patients with knee osteoarthritis compared with controls. ClinicoEconomics and Outcomes Research, 13, 421-435. https://doi.org/10.2147/ceor.s302289

  • Collier, T., Hughes, T., Chester, R., Callaghan, M., & Selfe, J. (2023). Prognostic factors associated with changes in knee pain outcomes, identified from initial primary care consultation data: A systematic literature review. Annals of Medicine, 55(1), 401-418. https://doi.org/10.1080/07853890.2023.2165706

  • Hunter, C., Deer, T., Jones, M., Chien, G., D’Souza, R., Davis, T., … & Strand, N. (2022). Consensus guidelines on interventional therapies for knee pain (STEP guidelines) from the American Society of Pain and Neuroscience. Journal of Pain Research, 15, 2683-2745. https://doi.org/10.2147/jpr.s370469

  • Kelly, T., Pazzol, M., & Darabad, R. (2023). Peripheral nerve stimulation in chronic knee pain: A case series. Cureus. https://doi.org/10.7759/cureus.50127

  • Shema-Shiratzky, S., Mor, A., & Elbaz, A. (2023). Untitled. Journal of Musculoskeletal Disorders and Treatment, 9(1). https://doi.org/10.23937/2572-3243/9/1

  • Sugai, K., Takeda‐Imai, F., Michikawa, T., Nakamura, T., Takebayashi, T., & Nishiwaki, Y. (2018). Association between knee pain, impaired function, and development of depressive symptoms. Journal of the American Geriatrics Society, 66(3), 570-576. https://doi.org/10.1111/jgs.15259

  • Tafler, L., Ovshaev, S., Ayon, S., & Luu, A. (2023). A novel knee traction technique to treat chronic knee pain. Cureus. https://doi.org/10.7759/cureus.43526