Upper gastrointestinal tract cancers

oesophageal cancer - Types ○ adenocarcinoma ( commonest now ) ○ squamous cell cancer ○ undifferentiated cancers ○ rare types eg melanoma , lymphoma , sarcomas Over 8000 diagnosed /year in UK Men more likely to be affected Five year survival rate is ~ 15 %. Risk factors ○ male sex ○ low socioeconomic status ○ smoking ○ excessive alcohol ○ GORD ○ Barrett's oesophagus ○ obesity ○ family hx of oesophageal , stomach , oral or pharyngeal cancer ○ high temp beverages and foods ○ low intake of fresh foods and vegetable Presentation can be variable- classical is dysphagia often with pain , acid reflux , loss of appetite and weight ( anaemia may occur )

dysphagia or aged 55 and over with weight loss and any of the following ○ upper abdominal pain ○ reflux ○ dyspepsia- Offer urgent direct access upper GI endoscopy to be done within 2 weeks

People aged 55 or over -treatment-resistant dyspepsia or upper abdominal pain with low haemoglobin levels or raised platelet count with any of the following ○ nausea ○ vomiting ○ weight loss ○ reflux ○ dyspepsia ○ upper abdominal pain or nausea and vomiting with any of the following...