Hidradenitis suppurativa

Hidradenitis suppurativa ( HS ) is a chronic , inflammatory , recurrent debilitating disease of the hair follicle that usually presents after puberty with painful , deep-seated , inflamed lesions in the apocrine gland bearing areas of the body , most commonly the axilla , inguinal and anogenital regions Also known as Verneuil's disease or acne inversa

Epidemiology- Prevalence appears to be 1 % to 4 % of the general population Occurs more commonly in women ( reports controversial ) Females more likely to have a family history and men had a tendency for more severe disease and associated acne Disease of the young- average age at presentation is 26 yrs for and 31 for No racial predilection

Cause- Cause unclear - complex disease Multifactorial and various factors can play a role as○ occlusion of the apocrine duct by a keratinous plug○ defects of follicular epithelium and bacterial overgrowth○ role of hormones- happens after puberty and can flare with menstrual cycle○ smoking - role of nicotine○ autoimmune - associated with certain disorders as thyroid disease , Inflammatory bowel disease, Sjogren's syndrome Acne vulgaris Obesity Athletes Genetic component Host defense defects Chemical irritants ( eg deodorants ) and mechanical irritation (...